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・ 257th Battalion, CEF
・ 257th Tunnelling Company
・ 258
・ 258 BC
・ 258 Tyche
・ 25801 Oliviaschwob
・ 25893 Sugihara
・ 258th (Canadien-Français) Battalion, CEF
・ 258th Aero Squadron
・ 258th Field Artillery Regiment
・ 258th Infantry Division (Wehrmacht)
・ 258th Tunnelling Company
・ 25 øre (World War II Danish coin)
・ 25-30 Alliance
・ 25-hydroxycholesterol 7α-hydroxylase
25-Hydroxyvitamin D3 1-alpha-hydroxylase
・ 25-pair color code
・ 25/8
・ 25/8 (song)
・ 250
・ 250 (number)
・ 250 BC
・ 250 Bettina
・ 250 Delaware Avenue
・ 250 Douglas Place
・ 250 Mannin no Kanken Wii de Tokoton Kanji Nou
・ 250 nanometer
・ 250 prosent
・ 250 Richmond Street West
・ 250 South Street


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25-Hydroxyvitamin D3 1-alpha-hydroxylase : ウィキペディア英語版
25-Hydroxyvitamin D3 1-alpha-hydroxylase

25-Hydroxyvitamin D3 1-alpha-hydroxylase (VD3 1A hydroxylase) also known as cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a cytochrome P450 enzyme that in humans is encoded by the ''CYP27B1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1594 )
VD3 1A hydroxylase is located in the proximal tubule of the kidney and a variety of other tissues, including skin (keratinocytes), immune cells, and bone (osteoblasts). The enzyme catalyzes the hydroxylation of Calcifediol to calcitriol (the bioactive form of Vitamin D):
:calcidiol + NADPH + H+ + O2 \rightleftharpoons calcitriol + NADP+ + H2O

Image:Calcidiol2.svg|Calcidiol
Image:Calcitriol.svg |Calcitriol

==Interactive pathway map==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「25-Hydroxyvitamin D3 1-alpha-hydroxylase」の詳細全文を読む



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